Publications by authors named "M Jayachandran"

Article Synopsis
  • Treating chronic bone illnesses can be very expensive, prompting a study to compare the costs of Jan Aushadhi (JA) medicines with both the cheapest and most expensive branded options in India.
  • The analysis examined 67 medications for various conditions, revealing that JA drugs are significantly cheaper; for example, some branded medications were over 32 times more expensive than JA alternatives.
  • The findings highlight the substantial cost savings possible by opting for JA medicines, making them a viable alternative for patients seeking affordable treatment for bone-related issues.
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Article Synopsis
  • Chemotherapy is crucial for cancer treatment but is often too expensive; the Indian government launched Jan Aushadhi (JAS) stores to provide affordable generic medicines.
  • The study aimed to compare the costs of chemotherapy regimens using JAS drugs, as well as the most and least expensive branded drugs in India.
  • Results showed substantial cost differences when using JAS drugs for chemotherapy across various types of cancers, indicating potential savings for patients.
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Key Points: Common kidney stones are unlikely to be an independent and direct cause of CKD in the general population. CKD may protect against kidney stones because of changes in key urinary factors critical for stone formation.

Background: Kidney stones and CKD are common disorders with a substantial interaction.

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Background: Senescence, a mechanism of cellular aging, which is characterized by irreversible proliferation arrest and a proinflammatory secretory phenotype, has been documented in women with preeclampsia. As cellular senescence can persist and progress, we postulated that it is associated with accelerated aging phenotype and accumulation of comorbidities in women with a history of preeclampsia.

Methods: We included a cohort of women with a history of preeclampsia (n=40) age- and parity-matched to a group of referent women with normotensive pregnancies (n=40).

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Non-alcoholic fatty liver disease (NAFLD) is by far the most prevalent form of liver disease worldwide. It's also the leading cause of liver-related hospitalizations and deaths. Furthermore, there is a link between obesity and NAFLD risk.

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