Publications by authors named "M Jank"

Purpose: Circular RNAs (circRNAs) are stable, non-coding RNAs with tissue- and developmental-specific expression making them suitable biomarkers for congenital anomalies. Current circRNA discovery pipelines have focused on human and mouse. We aim to bridge this gap by combining bioinformatics resources and used circtial1 as a model candidate in the nitrofen rat model of congenital diaphragmatic hernia (CDH).

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Many dental homecare products are marketed, several of which have been evaluated using a "clean tooth" protocol (the teeth are scaled at the start of the trial). The efficacy of dental products in dogs that have not had their teeth professionally cleaned ("dirty tooth model") has been studied far less often. Some dogs for which professional dental cleaning is indicated will not have their teeth cleaned because of anesthetic risk or for other reasons.

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Article Synopsis
  • - The study investigated the effects of an individualized computerized cognitive training (iCCT) using machine learning on cognitive abilities in older adults with mild cognitive impairment (MCI), comparing it to a basic version (bCCT) over six months! - Participants in the iCCT group showed a significant improvement in cognitive scores (average increase of 2.2 points) compared to those in the bCCT group (average increase of 0.9 points) based on the Montreal Cognitive Assessment (MoCA) results! - Both groups experienced cognitive enhancement, but the iCCT group demonstrated a more substantial improvement, indicating that personalized training may be more effective for individuals with MCI!
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Worldwide, 150 children are born each day with congenital diaphragmatic hernia (CDH), a diaphragmatic defect with concomitant abnormal lung development. Patients with CDH with large defects are particularly challenging to treat, have the highest mortality, and are at significant risk of long-term complications. Advances in prenatal and neonatal treatments have improved survival in high-risk patients with CDH, but surgical treatment of large defects lacks standardization.

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