Publications by authors named "M Jamal Hajjar"
Article Synopsis
- The study reviewed biotinidase gene variants in a large group of women undergoing reproductive carrier screening to improve management of those with significant gene changes.
- About 6.1% of the 91,637 women tested had pathogenic or likely pathogenic variants, with a specific variant (D444H) being the most common in 92.3% of cases.
- The results showed variations in heterozygote rates among different racial and ethnic groups, highlighting the potential for reproductive carrier screening to lead to earlier diagnoses compared to traditional newborn screening methods.
Background: The association between anemia and severity of infection as well as mortality rates among patients infected with COVID-19 has scarcely been studied. This is the first study from the UAE aimed to assess the influence of anemia on COVID-19 severity, ICU admission, and mortality rate.
Methods: A retrospective chart review of hospitalized COVID-19 patients was conducted in a large COVID-19 referral hospital in UAE.
Objectives: Early identification and fluid resuscitation are recognized performance measures within sepsis care. Despite fluid resuscitation, fluid goals are often not achieved in the prehospital environment. Furthermore, description of implementation process and evaluation of implementation success are historically underreported in prehospital research.
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- Polycyclic aromatic hydrocarbons (PAHs), especially benzo(a)pyrene (B(a)P), are harmful environmental contaminants linked to serious health issues like cancer and immune system suppression.
- This study investigates the use of extracellular vesicles (EVs) and their microRNA (miRNA) content as potential biomarkers for PAH exposure, focusing on changes in EV production and miRNA profiles following exposure to B(a)P.
- The findings show that B(a)P exposure increases EV production and specifically regulates the expression of miR-342-3p, suggesting that EVs and miRNAs could serve as valuable indicators of PAH exposure in toxicological assessments.
Objectives: The present study aims to examine the hypothetical model of the relationship between food insecurity and Non-alcoholic fatty liver disease (NAFLD) in a sample of Iranian adults.
Methods: In this cross-sectional study, 275 subjects (18-70 years old) who met the inclusion criteria were recruited. Fatty liver was diagnosed by abdominal ultrasonography, and eligible patients underwent liver fibro scan assessment to determine fibrosis and steatosis.