COVID-19, school closures, and student learning outcomes. New global evidence from PISA.

The COVID-19 pandemic resulted in significant disruption in schooling worldwide. Global test score data is used to estimate learning losses by modeling the effect of school closures on achievement by predicting the deviation of the most recent results from a linear trend using data from all rounds of PISA. Mathematics scores declined an average of 14 percent of a standard deviation, roughly equal to seven months of learning.

Zinc-doped hydroxyapatite as a pH responsive drug delivery system for anticancer drug 6-mercaptopurine.

6-Mercaptopurine (6MP) is commonly used in the treatment of acute lymphoblastic leukemia as an important agent in maintenance therapy. Despite its therapeutic benefits, 6MP has some limitations during therapy. Taking into account the disadvantages during 6MP therapy, there is a great need to create an appropriate delivery system for this drug.

Double Hydroxyl Salt as Smart Biocompatible pH-Responsive Carrier for 6-Mercaptopurine.

Hydroxy double salts are layered materials that are considered to be biocompatible. For this reason, research has been initiated on the possibility of their use in drug delivery. Despite their use for several types of drugs, their potential for controlled release of mercaptopurine (MERC) has not been studied.

Titanium modification using bioactive titanate layer with divalent ions and coordinated ciprofloxacin - Assessment of drug distribution using FT-IR imaging.

The paper presents a new method of titanium alloy (Ti6Al4V) modification using bioactive titanate layers containing various divalent ions (Ca, Mg, Sr, Zn) and surface-coordinated ciprofloxacin. Due to the coordination of ciprofloxacin (antibiotic) on the surface of the alloy, it has great application potential. In the paper, the influence of a given cation on the effectiveness of drug sorption was determined.