Publications by authors named "M Jagannath"

Obstructive sleep apnea (OSA) is a disorder which blocks the upper airway during sleep. The severity of OSA will lead heart attack, stroke and end of life. This proposed study explored the classification of OSA and healthy subjects using brain connectivity analysis from electroencephalogram (EEG) signals.

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For the last few months, the world has been under an astringent lockdown due to COVID-19. The number of COVID-19 cases is incrementing steadily. Even though scientists have found a vaccine for the obviation of the virus, the threat of being affected is high when we head out.

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Breast cancer is one among the most frequent reasons of women's death worldwide. Nowadays, healthcare informatics is mainly focussing on the classification of breast cancer images, due to the lethal nature of this cancer. There are chances of inter- and intra-observer variability that may lead to misdiagnosis in the detection of cancer.

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Background: Elevated glucose concentrations lead to increased insulin secretion and suppression of glucagon secretion. In fact, insulin is a physiological inhibitor of glucagon secretion. Type 2 diabetes mellitus (T2DM) patients have defects in insulin secretion.

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Article Synopsis
  • Retinoid X Receptors (RXR) play important roles in regulating metabolism, and rexinoids that activate RXR are being explored as treatments for metabolic syndrome; however, some past rexinoids caused adverse effects like increased triglycerides and liver issues.
  • This study focuses on evaluating a new rexinoid, CNX-013-B2, for treating metabolic syndrome by selectively activating specific RXR partner pathways to improve insulin resistance.
  • Results showed that CNX-013-B2 led to significant reductions in glucose and cholesterol levels in both ob/ob and high-fat diet mice, suggesting its potential benefits for managing metabolic risk factors.
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