Publications by authors named "M Jacob Schrader"
Patients with end-stage kidney disease (ESRD) represent a high-risk population in terms of both development of and death by cardiovascular diseases. Outcome data of ESRD patients with severe aortic valve stenosis (AS) treated by transcatheter aortic valve implantation (AVI) are scarce. We aim to compare the outcome of ESRD patients undergoing transfemoral (TF) or transapical (TA) AVI.
View Article and Find Full Text PDFNeurorehabilitation is characterized by a structured, interdisciplinary collaboration among various professional fields, focused on achieving individualized participation goals for patients. This process considers the different levels of the International Classification of Functioning, Disability, and Health (ICF), specifically function, activity and participation. Multiple evidence-based treatment procedures targeting specific mechanisms of action are available for the rehabilitation of disorders associated with various diseases.
View Article and Find Full Text PDFArticle Synopsis
- Filamentous microorganisms, like fungi, have complex structures made up of branched hyphae, and accurately measuring the mechanical properties of these hyphae is essential for understanding their behavior.
- This study introduces a novel microfluidic system that measures the bending stiffness of individual fungal hyphae more accurately by positioning the samples away from interfering walls, resulting in better measurement outcomes.
- The findings indicate that the bending stiffness of certain hyphae is significantly higher than previously recorded, while the Young's Modulus, describing the cell wall elasticity, shows similar values across different fungal types, aiding future research on how cultivation conditions affect hyphal properties and overall fungus behavior.
Acyl-CoA binding domain-containing proteins (ACBDs) perform diverse but often uncharacterised functions linked to cellular lipid metabolism. Human ACBD4 and ACBD5 are closely related peroxisomal membrane proteins, involved in tethering of peroxisomes to the ER and capturing fatty acids for peroxisomal β-oxidation. ACBD5 deficiency causes neurological abnormalities including ataxia and white matter disease.
View Article and Find Full Text PDF