Pre-clinical methods to evaluate photic phenomena in intraocular lenses.

A new system and methodology are introduced to evaluate photic phenomena induced by different intraocular lens (IOL) technologies using a "see-through" IOL analyzer system in phakic subjects. Nineteen phakic subjects looked through the Groningen IOL Telescope type 1 (GIT1) system under different conditions. Four different IOL designs with different clinical levels of photic phenomena were evaluated by the subjects.

Effect of Correcting Peripheral Refractive Errors on Retinal Sensitivity in Younger and Older Healthy Adults.

Significance: Retinal sensitivity decreases with age and age-related eye diseases. Peripheral retinal sensitivity may also be compromised if the refractive correction is not optimized for peripheral vision.

Purpose: This study aimed to determine the impact of using a peripheral refractive correction on perimetric thresholds and the influence of age and spherical equivalent on this impact.

Effect of Violet Light-Filtering and Manufacturing Improvements in an Extended Depth-of-Focus Intraocular Lens on Visual Performance.

Purpose: To assess the experimental visual performance and dysphotopsia characteristics of the new Tecnis Symfony OptiBlue extended-depth-of-focus with violet light-filtering (ZXR00V) intraocular lens (IOL) compared with the colorless Tecnis Symfony (ZXR00) IOL.

Methods: Range of vision was assessed with simulated visual acuity defocus curves, predicted by white light through focus modulation transfer function (MTF) measurements. The clinical visual acuity defocus curve of the ZXR00 IOL was used to validate the predicted range of vision.

Degradation of Visual Performance With Increasing Levels of Retinal Stray Light.

Purpose: To quantify the effect of induced stray light on halo size, luminance threshold, and contrast sensitivity.

Methods: Retinal stray light was induced in five healthy subjects using different photographic filters. The stray light induced ranged from levels observed in intraocular lenses (IOLs) with glistenings (low) to cataract level (high).

Effect of the equivalent refractive index on intraocular lens power prediction with ray tracing after myopic laser in situ keratomileusis.

Purpose: To determine the impact of the equivalent refractive index (ERI) on intraocular lens (IOL) power prediction for eyes with previous myopic laser in situ keratomileusis (LASIK) using custom ray tracing.

Setting: AMO B.V.