Objective: To describe 24-hour physical activities (sleep and physical activity) in adults with cerebral palsy (CP), explore potential influencing factors and compare 24-hour physical activities with controls.
Design: Cross-sectional, observational internet study involving adults with CP and a convenience sample of adults without CP.
Setting: Individuals residing in the Netherlands Participants: 110 adults with CP (median age 42, range 28-77 years; 64 (58%) ambulant; 40% male) and 89 adult controls (median age 43, range 18-78 years; 29% male).
Introduction: Chronic postsurgical pain (CPSP) represents a widely underdiagnosed and often poorly treated medical problem, affecting 10-50% of all surgical patients, exhibiting neuropathic features in 35-60%. It is hypothesised that surgery-induced tissue damage and the subsequent immune response cause sensory alterations in the early postoperative period, ultimately leading to a chronic neuropathic or nociplastic pain state. The 'Sensory Changes and Immunological parameters in Postsurgical pain' study (SCIP-Pain study) was designed to test this hypothesis and identify sensory alterations and changes in the immunological response that are related to the development of CPSP with neuropathic features.
View Article and Find Full Text PDFUnderstanding prenatal alcohol exposure (PAE) risk perception is important for the communication and prevention of alcohol use during pregnancy. A previous systematic review has explored the dimensions and influencing factors of women's PAE risk perceptions, leading to the construction of Pregnancy Alcohol Use Risk Perception (PARP) conceptual model. This study aims to refine the PARP model using a Delphi process.
View Article and Find Full Text PDFWhile some of the 17 Sustainable Development Goals (SDGs) rely on the support of established international organizations and regimes, others lack strong institutions in their governance areas. This raises the question of whether the SDGs can contribute to strengthening these less institutionalized areas in global governance, which would make these goals important factors in advancing international institutionalization. We study this question with a focus on SDG 12, which targets sustainable consumption and production.
View Article and Find Full Text PDFThis work explores techniques for accurately modeling the propagation of ultrasound waves in lossy fluid-solid media, such as within transcranial ultrasound, using the spectral-element method. The objectives of this work are twofold, namely, (1) to present a formulation of the coupled viscoacoustic-viscoelastic wave equation for the spectral-element method in order to incorporate attenuation in both fluid and solid regions and (2) to provide an end-to-end workflow for performing spectral-element simulations in transcranial ultrasound. The matrix-free implementation of this high-order finite-element method is very well-suited for performing waveform-based ultrasound simulations for both transcranial imaging and focused ultrasound treatment thanks to its excellent accuracy, flexibility for dealing with complex geometries, and computational efficiency.
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