Effects of desflurane and mode of ventilation on cardiovascular and respiratory functions and clinicopathologic variables in horses.

Objective: To quantitate the effects of desflurane and mode of ventilation on cardiovascular and respiratory functions and identify changes in selected clinicopathologic variables and serum fluoride values associated with desflurane anesthesia in horses.

Animals: 6 healthy adult horses.

Procedure: Horses were anesthetized on 2 occasions: first, to determine the minimum alveolar concentration (MAC) of desflurane in O2 and second, to characterize cardiopulmonary and clinicopathologic responses to 1X, 1.

Effects of sevoflurane dose and mode of ventilation on cardiopulmonary function and blood biochemical variables in horses.

Objective: To quantitate effects of dose of sevoflurane and mode of ventilation on cardiovascular and respiratory function in horses and identify changes in serum biochemical values associated with sevoflurane anesthesia.

Animals: 6 healthy adult horses.

Procedure: Horses were anesthetized twice: first, to determine the minimum alveolar concentration (MAC) of sevoflurane and second, to characterize cardiopulmonary and serum biochemical responses of horses to 1.

Effects of xylazine hydrochloride during isoflurane-induced anesthesia in horses.

Objective: To quantitate dose- and time-related anesthetic-sparing effects of xylazine hydrochloride (XYL) during isoflurane-induced anesthesia in horses and to characterize selected physiologic responses of anesthetized horses to administration of XYL.

Animals: 6 healthy adult horses.

Procedure: Horses were anesthetized 2 times to determine the minimum alveolar concentration (MAC) of isoflurane in O2 and to characterize the anesthetic-sparing effect (MAC reduction) after IV administration of XYL (0.

Morphologic changes and xanthine oxidase activity in the equine jejunum during low flow ischemia and reperfusion.

Objective: To determine whether xanthine oxidase and dehydrogenase activities are altered during low flow ischemia and reperfusion of the small intestine of horses.

Animals: 5 clinically normal horses without histories of abdominal problems.

Procedure: With the horse under general anesthesia, a laparotomy was performed and blood flow to a segment of the distal jejunum was reduced to 20% of baseline for 120 minutes and was then reperfused for 120 minutes.