Publications by authors named "M J Witvliet"
Article Synopsis
- * Conducted across 26 children's hospitals in the US from March 2020 to May 2023, the research involved analyzing data from over 172,000 eligible children and young adults aged 5 to 20 with confirmed COVID-19.
- * The findings aim to establish a clear association between pre-infection BMI categories—ranging from healthy weight to severe obesity—and the likelihood of experiencing PASC, with statistical analyses adjusting for various demographic and clinical
The Diagnostic Accuracy of Serum Alpha-Fetoprotein Levels in Follow-up for Recurrence of Sacrococcygeal Teratoma; a Nationwide Review of SCT Cases in the Netherlands.
J Pediatr Surg
September 2024
Background: Serum alpha-fetoprotein (AFP) is often used as tumour marker for recurrent sacrococcygeal teratoma (SCT). We aimed to assess the normal dynamics of serum AFP levels after initial resection and diagnostic accuracy of serum AFP levels the follow-up for recurrence in SCT.
Methods: This retrospective study included 57 patients treated for SCT in the six pediatric surgical centers in the Netherlands from 1980 to 2018.
Article Synopsis
- The BNT162b2 vaccine was effective in preventing COVID-19 infection among adolescents during the Delta variant period, showing a 98.4% effectiveness without significant waning after the first dose.
- During the Omicron period, the vaccine's effectiveness decreased to 74.3% against infections in children, while still providing strong protection against severe disease and ICU admissions.
- The study involved a large sample size across different age groups and carefully assessed potential risks related to vaccination, especially concerning cardiac complications, and found no increased risk.
Background: The coronary artery calcium (CAC) score can be used to increase (CAC score > 0) or decrease (CAC score = 0) the likelihood of coronary artery disease (CAD). We compared the CAC score with the pre-test probability (PTP) for CAD (low, intermediate, and high). Furthermore, we compared the CAC score with exercise electrocardiography (ECG) and compared both tests with coronary angiography.
View Article and Find Full Text PDFArticle Synopsis
- - The RECOVER-Pediatrics study aims to investigate the prevalence and long-term effects of Long COVID (PASC) in children and young adults, addressing the need for more research in this area.
- - The study recruits caregiver-child pairs and young adults across 100+ sites in the U.S., focusing on a diverse group of participants with and without prior SARS-CoV-2 infections, and will collect data over several years through various tiers of assessments.
- - The ultimate goal of the study is to understand the clinical trajectory, mechanisms, and sociodemographic factors related to pediatric PASC, thereby contributing to potential treatments and public health responses.