Publications by authors named "M J Warnier"

Purpose: The Awake Breathing Pattern Assessment (ABPA) is a prototypical clinical grid recently designed through an international consensus of Speech and Language Pathologists (SLPs) to categorize the awake and habitual breathing pattern during the orofacial myofunctional assessment. This cross-sectional study aims to explore the psychometric properties of the ABPA in a preschool population.

Methods: 133 children from 2;11 to 6 years old were assessed with the ABPA.

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Purpose: mouth breathing (MB) has detrimental effects on children's growth. Diagnosis of MB is possible through a multidisciplinary approach including Speech-Language Pathologist's (SLP) assessment; however, SLPs currently have little to no defined selection criteria to determine the awake and habitual breathing pattern. This study aims at identifying relevant criteria for the assessment of the habitual and awake breathing pattern of preschool children, and developing a grid that would help SLPs diagnose MB in their clinical practice.

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Article Synopsis
  • Pancreatic cancer is highly lethal, primarily due to late diagnosis and strong treatment resistance, with no significant advancements in patient care despite increased understanding of the disease over the past twenty years.
  • Research indicates that treatment methods, like gemcitabine, can induce a senescent-like state in resistant pancreatic cancer cells, contributing to their survival and resistance to further treatments.
  • Combining gemcitabine with the senolytic compound ABT-263 effectively reduced tumor growth in preclinical models, suggesting that targeting senescent-like cancer cells could improve the effectiveness of traditional chemotherapy, warranting further exploration in clinical trials.
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In response to many stresses, such as oncogene activation or DNA damage, cells can enter cellular senescence, a state of proliferation arrest accompanied by a senescence-associated secretory phenotype (SASP). Cellular senescence plays a key role in many physiopathological contexts, including cancer, aging and aging-associated diseases, therefore, it is critical to understand how senescence is regulated. Calcium ions (Ca) recently emerged as pivotal regulators of cellular senescence.

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There is a general need for more knowledge on the development of French phonology, and little information is currently available for typically developing French-speaking three-year-old children. This study took place in Belgium and explores the accuracy of speech production of 34 typically developing French-speaking children using a picture naming task. Measures of speech accuracy revealed lower performance than previously seen in the literature.

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