Publications by authors named "M J W de Bruijn"
Embryonic hematopoietic cells develop in the fetal liver (FL), surrounded by diverse non-hematopoietic stromal cells. However, the spatial organization and cytokine production patterns of the stroma during FL development remain poorly understood. Here, we characterized and mapped the hematopoietic and stromal cell populations at early (E12.
View Article and Find Full Text PDFBackground And Objectives: Anti-NMDA receptor (anti-NMDAR) encephalitis generally manifests in young adults. Although 80%-90% returns to independence, the majority experience persistent cognitive and psychosocial difficulties. Studies have demonstrated that cognitive recovery may continue for years; the temporal trajectory is largely unknown, as are factors influencing cognitive/psychosocial recovery.
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- The study aimed to evaluate the efficacy of shortening the cast immobilization period for distal radius fractures (DRF) from 3-5 weeks to 1 week followed by gradual mobilization.
- Conducted in various trauma centers, it involved randomly assigning hospitals to either the usual care or the shorter immobilization method, with patients aged 18 to 85 included if they had isolated, non- or minimally displaced DRF.
- Results showed no significant differences in functional outcomes, pain scores, or patient satisfaction between the two groups, suggesting that the shorter immobilization period may be equally effective as the conventional approach.
Background And Objectives: Autoimmune encephalitis (AIE) and paraneoplastic neurologic syndromes (PNSs) encompass a heterogeneous group of antibody-associated disorders. Both the number of syndromes and commercially available antibody tests have increased considerably over the past decade. High-quality population-based data on epidemiology of these disorders and real-world performance of antibody tests are needed.
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