Publications by authors named "M J V Hoffer"
Ménière's disease (MD) is characterized by loss of balance and hearing disorders. Although there is known to be endolymphatic hydrops involved in the pathological process, the pathogenesis of the disease is still largely unclear. Approximately half of patients with MD suffer from depressive symptoms and high levels of several stress hormones were observed in MD and depression, simultaneously.
View Article and Find Full Text PDFThe severity of SARS-CoV-2 illness is influenced by factors including age, sex, pre-existing health conditions, and individual immune responses. However, the mechanisms conferring immunity following antigenic challenge have not been fully elucidated. There are currently no studies evaluating longitudinal proteomic changes in individuals following vaccination and breakthrough, limiting our understanding of the underlying mechanisms driving conferred immunity.
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- Confined placental mosaicism (CPM) can lead to serious pregnancy complications, and non-invasive prenatal testing (NIPT) can help identify these cases.
- A study analyzed the mosaic ratios from NIPT in 122 CPM cases to see if they could predict negative pregnancy outcomes like fetal growth restriction (FGR) or preterm birth.
- Results indicated that a higher mosaic ratio was linked to worse outcomes, but there wasn't a specific threshold to use for predicting individual cases of CPM.
Tricuspid Annular Plane Systolic Excursion (TAPSE) in COPD Patients, A Systematic Review and Meta-Analysis.
Clin Exp Emerg Med
September 2024
Introduction: Tricuspid annular plane systolic excursion (TAPSE) is an echocardiographic parameter that serves as a prognostic indicator for severity of COPD clinical course. This study, consisting of a systematic review and meta-analysis, evaluates the current literature to elucidate the relationship between TAPSE measurement in COPD patients versus control subjects to discern baseline evidence of right heart strain.
Methods: PubMedTM, ScopusTM, CINAHL, Web of Science, and Cochrane Review databases were searched from their beginning through November 1, 2023, for eligible studies.