Photodynamic and antibacterial studies of template-assisted FeO-TiO nanocomposites.

FeO-TiO (FT) nanocomposites were successfully synthesized by template-assisted precipitation reaction using Polyvinylpyrrolidone-Polyethylene glycol (PVP-PEG), Tween-80 (T-80) and Cetyltrimethylammomium bromide (CTAB) as templates. The prepared nanocomposites were characterized by XRD, SEM, EDX, UV-DRS, FT-IR, and FT-Raman spectroscopic analysis. The photohemolysis studies were done in human erythrocytes and the cell viability studies were done in HeLa cell lines under the irradiation of an LED light source.

Comparison of the uptake of untargeted and targeted immunostimulatory nanoparticles by immune cells in the microenvironment of metastatic breast cancer.

To alter the immunosuppressive tumor microenvironment (TME), we developed an immunostimulatory nanoparticle (NP) to reprogram a tumor's dysfunctional and inhibitory antigen-presenting cells (APCs) into properly activated APCs that stimulate tumor-reactive cytotoxic T cells. Importantly, systemic delivery allowed NPs to efficiently utilize the entire microvasculature and gain access into the majority of the perivascular TME, which coincided with the APC-rich tumor areas leading to uptake of the NPs predominantly by APCs. In this work, a 60 nm NP was loaded with a STING agonist, which triggered robust production of interferon β, resulting in activation of APCs.

Enhanced photocatalytic and photodynamic activity of chitosan and garlic loaded CdO-TiO hybrid bionanomaterials.

Herein, the work addresses the synthesis of biomaterials (chitosan and garlic) loaded CdO-TiO hybrid nanocomposites for photocatalytic water treatment and photodynamic cancer therapeutic applications that were reported the first time. CdO-TiO (CT) nanocomposites were synthesized and loaded with the biomaterials such as chitosan and garlic by simple sol-gel method. The nanomaterials were characterized and the photodegradation of three model pollutants, Methylene blue (MB), Methyl orange (MO) and Rhodamine B (Rh-B) was opted to investigate the efficiency of the synthesized photocatalyst under the solar light.

Biomaterial (Garlic and Chitosan)-Doped WO-TiO Hybrid Nanocomposites: Their Solar Light Photocatalytic and Antibacterial Activities.

In this work, WO-TiO, chitosan-blended WO-TiO, and garlic-loaded WO-TiO nanocomposites were synthesized by the sol-gel and precipitation technique. The synthesized nanocomposites were characterized by XRD, FE-SEM, HR-TEM, EDX, UV-DRS, FT-IR, and TG-DTA analysis. The photocatalytic efficiency of the three synthesized nanocomposites on the degradation of dyes such as rhodamine B (Rh-B), methylene blue (MB), and methyl orange (MO) as organic pollutants was evaluated under solar light irradiation.

A study on stability analysis of atrial repolarization variability using ARX model in sinus rhythm and atrial tachycardia ECGs.

Background: The interaction between the PTa and PP interval dynamics from the surface ECG is seldom explained. Mathematical modeling of these intervals is of interest in finding the relationship between the heart rate and repolarization variability.

Objective: The goal of this paper is to assess the bounded input bounded output (BIBO) stability in PTa interval (PTaI) dynamics using autoregressive exogenous (ARX) model and to investigate the reason for causing instability in the atrial repolarization process.