A roadmap for model-based bioprocess development.

The bioprocessing industry is undergoing a significant transformation in its approach to quality assurance, shifting from the traditional Quality by Testing (QbT) to Quality by Design (QbD). QbD, a systematic approach to quality in process development, integrates quality into process design and control, guided by regulatory frameworks. This paradigm shift enables increased operational efficiencies, reduced market time, and ensures product consistency.

Design and Development of an Edible Coating for a Ready-to-Eat Fish Product.

The application of chitosan and alginate coatings for a ready-to-eat (RTE) baked fish product was studied. An experimental design was used to investigate the effect of coating a polysaccharide concentration and glycerol addition on the safety (microbial growth) and quality (water loss and lipid oxidation) of an RTE fish product under optimal and abused storage conditions. The results showed that a chitosan coating with 1% (/) chitosan in 1% (/) acetic acid and 15% (/ chitosan) glycerol, or a 1% (/) alginate coating with no glycerol and no crosslinking, showed the best performance in controlling the tested safety and quality parameters.

A multi-purpose pilot-scale molten metal & molten salt pyrolysis reactor.

This paper describes the design features and operational details of a molten metal pyrolysis reactor. Such a reactor allows pyrolysis experimentation on biomass, aluminium-laminated plastics, mixed plastics, carbon fibre materials, etc. Experimental results on biodegradable plastic, carbon fibre composites, biomass and printed circuit boards (PCBs) are presented.

Recycling of aluminium laminated pouches and Tetra Pak cartons by molten metal pyrolysis - Pilot-scale experiments and economic analysis.

Aluminium laminated (AL) pouch packages and aluminium laminated Tetra-Pak cartons are considered unrecyclable, reducing their otherwise excellent lifecycle performance. This paper describes experimental results on pilot plant trials to recycle AL packages with a molten metal pyrolysis reactor. The experimental evidence shows that both package formats can be recycled and that clean aluminium can be recovered.

Economic assessment of a 40,000 t/y mixed plastic waste pyrolysis plant using direct heat treatment with molten metal: A case study of a plant located in Belgium.

Pyrolysis has been identified as an ideal process to recycle mixed plastic waste (MPW). This study investigates the economics of a 40,000 t/y MPW pyrolysis process, called PlastPyro, located in Belgium, to an accuracy of ±15% i.e.