Publications by authors named "M J Somerville"

Background: Precursor-level safety events (PSEs) pose greater patient risk than no-harm events but are not as severe as serious safety events. Despite their potential for harm, the underlying determinants associated with PSEs are poorly understood. This study aimed to use a behavior change framework to understand the underlying determinants of PSEs and whether associated action items aligned with the behavior.

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The rapid pace of development and application of digital technology and data science, including artificial intelligence (AI), is transforming our world. In this chapter, we address the question: "Is bioethics relevant to how we should develop, govern, and use AI in healthcare, specifically in neurosurgery?" We recognize that medical decision-making involves uncertainty and is complex, and predicting potential outcomes is difficult. We conclude that the use of AI in neurosurgery is not inherently unethical.

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Article Synopsis
  • Computational neurosurgery combines artificial intelligence and computational modeling to enhance the diagnosis and treatment of neurosurgical conditions, aiming to advance clinical neurosciences.
  • The field seeks to integrate ethical considerations to ensure that the use of AI is conducted responsibly and prioritizes patient care, ultimately aiming to prevent errors in treatment.
  • This initiative serves as a guide for practitioners, ethicists, and scientists in the application of ethical standards within computational neurosurgery.
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Article Synopsis
  • The study investigates changes in the optic nerve head and retina of brain-dead organ donors after varying durations of elevated intraocular pressure (IOP).
  • Researchers examined optic and retinal tissues from three donors, revealing significant differences in protein and mRNA expression related to astrocytic markers and inflammation depending on the duration of IOP elevation.
  • Findings suggest that longer periods of elevated IOP lead to more pronounced changes in both the optic nerve and retina, and highlight the potential of using this model for further understanding the mechanotranscriptomic responses in eye conditions.
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Existing barriers to care were exacerbated by the development and implementation of necessary public health restrictions during the COVID-19 pandemic. Children with complex care needs and their families represent a small portion of the paediatric population, and yet they require disproportionately high access to services. Little is known about the impact of COVID-19 public health measures on this population.

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