Publications by authors named "M J Selvamani"
Article Synopsis
- Dopamine is a crucial neurotransmitter that impacts movement, cognition, and emotions, with abnormal levels tied to various mental disorders and diseases.
- Zinc sulfide (ZnS) nanostructures, known for their unique electrochemical properties, are effectively produced using the hydrothermal method, which creates structures with large surface areas and enhanced performance.
- The study focuses on synthesizing starfish-shaped ZnS nanostructures and evaluating their potential as a sensor for dopamine, confirming their crystalline structure and morphology through advanced imaging and analysis techniques.
Article Synopsis
- - The study focuses on synthesizing manganese(III) oxide (MnO), characterizing its structure, and analyzing its electrochemical properties, particularly in relation to dopamine detection, which is significant for medical diagnostics.
- - MnO is synthesized using manganese sulfate and potassium permanganate in deionized water, followed by a series of heating and drying processes in a sealed autoclave to form hierarchical rod-like structures.
- - Characterization techniques such as X-ray diffraction (XRD) and field emission scanning electron microscopy (FE-SEM) confirm the crystalline structure and 100 nm particle size of MnO, while cyclic voltammetry tests indicate improved sensing ability of the modified electrode compared to a bare electrode.
Background The article delineates a strategy for detecting ascorbic acid (AA) through the use of iron oxide (Fe₂O₃) nanoparticles on an electrode. The Fe₂O₃ nanoparticles demonstrated effective electrocatalysis in the oxidation of AA, resulting in increased peak currents. The sensor showcased a wide linear detection range, a low detection limit, and high selectivity towards interferents, making it suitable for accurate AA measurement in food analysis and medical diagnostics applications.
View Article and Find Full Text PDFBackground In recent years, significant advancements have been made in various scientific sectors, particularly in healthcare and pharmaceutical research. This progress has been driven by the development of enhanced sensing materials and methodologies. Electrochemical sensing has become an important tool in detecting and analyzing drug molecules due to its high sensitivity, specificity, and rapid response times.
View Article and Find Full Text PDFArticle Synopsis
- - This study investigates the anti-metastatic effects of a flowering plant known as wild heliotrope on MCF-7 breast cancer cells, focusing on its ability to disrupt key signaling pathways.
- - Using an MTT assay, the research found that the plant extract significantly inhibited cell growth, with maximum inhibition observed at a concentration of 150 μg/mL, and it suppressed important pathways like GSK3β and Wnt2.
- - The findings suggest that the plant may serve as a potential anticancer agent against breast cancer, indicating further evaluation could be beneficial for different breast cancer types and cell lines.