Publications by authors named "M J Piskorz"
Background: Irritable bowel syndrome (IBS) is influenced by various factors, including socioemotional stressors. The COVID-19 lockdown created a unique environment characterized by reduced social interactions, potentially impacting IBS symptoms.
Aim: To assess how lockdown measures affected symptoms related to the gut-brain axis in IBS patients in Buenos Aires, Argentina.
Article Synopsis
- COVID-19 patients often show abnormal immune responses and mental health issues during hospitalization, but the connection with gut microbiome has not been fully explored.
- The study classified COVID-19 severity into three levels: low (27.4%), moderate (29.8%), and critical (42.8%), with common symptoms including fever (66.1%) and cough (55.6%), and notable rates of anxiety (27.3%) and depression (39%).
- Findings indicate that more severe cases exhibited higher levels of systemic inflammation and reduced gut bacterial diversity, particularly in women and obese individuals, suggesting a relationship between gut health, mental health, and COVID-19 severity, pointing to the potential of using microbiome-focused treatments.
As the involvement of the intestinal microbiota in the etiopathology of irritable bowel syndrome, subtype diarrhoea (IBS-D) is now increasingly recognised, a preliminary, quasi-experimental, before-after and prospective study was conducted on 28 patients to test the effect of a tannin-based supplement on the composition and activity of the microbiota, after 8 weeks of treatment. No statistically significant differences were found in α- or β-diversity. However, sparse Partial Least Squares Discriminant Analysis (sPLS-DA) and Boruta algorithm did reveal significant changes in the relative abundance of specific groups of bacteria, highlighting the involvement of recognized of IBS-D biomarkes, namely (adj = 3.
View Article and Find Full Text PDFLatin American consensus on diagnosis of gastroesophageal reflux disease.
Neurogastroenterol Motil
March 2024
Article Synopsis
- Diagnosing gastroesophageal reflux disease (GERD) can be complex due to its varied symptoms and causes, with esophageal acid exposure time (AET) via pH-metry being the gold standard method.
- A group of 15 experts from nine countries reviewed current literature and utilized a structured grading system to recommend which diagnostic tools are most effective for GERD.
- Key findings suggest that a trial with proton pump inhibitors (PPI) is suitable for patients with heartburn but not for those with other symptoms; endoscopic results indicating erosive esophagitis paired with abnormal pH testing are the most reliable methods for confirming GERD.
Background: A retromolar canal (RMC) is an anatomical variation of the mandibular canal located in the retromandibular area. Retromolar canals and their contents may be of great clinical importance for clinicians dealing with the discussed region. The analysis of the available literature indicates that RMC is not a rare phenomenon.
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