Publications by authors named "M J Pecha"

The large COVID-19 outbreaks in prisons in the Washington (USA) State Department of Corrections (WADOC) system during 2020 highlighted the need for a new public health approach to prevent and control COVID-19 transmission in the system's 12 facilities. WADOC and the Washington State Department of Health (WADOH) responded by strengthening partnerships through dedicated corrections-focused public health staff, improving cross-agency outbreak response coordination, implementing and developing corrections-specific public health guidance, and establishing collaborative data systems. The preexisting partnerships and trust between WADOC and WADOH, strengthened during the COVID-19 response, laid the foundation for a collaborative response during late 2021 to the largest tuberculosis outbreak in Washington State in the past 20 years.

View Article and Find Full Text PDF
Article Synopsis
  • During 2014-2020, Washington state prisons reported no cases of tuberculosis (TB), but from July 2021 to June 2022, 25 TB cases emerged, indicating a significant outbreak linked to closely related bacteria strains among incarcerated individuals.
  • The outbreak involved a median infectious period of 170 days for contagious patients, leading to the identification of over 3,000 contacts, with 244 diagnosed with latent TB infection (LTBI) due to delayed case detection.
  • The lack of annual TB screening during the pandemic and fear of isolation contributed to the outbreak, highlighting the need for ongoing collaboration between the Washington State Department of Corrections and the Washington State Department of Health to manage and prevent future TB cases.
View Article and Find Full Text PDF

Progress towards TB elimination in the United States will require improved detection and treatment of latent TB infection among non-U.S.-born residents who remain at disproportionate risk of TB disease.

View Article and Find Full Text PDF

Lignin solvolysis from the plant cell wall is the critical first step in lignin depolymerization processes involving whole biomass feedstocks. However, little is known about the coupled reaction kinetics and transport phenomena that govern the effective rates of lignin extraction. Here, we report a validated simulation framework that determines intrinsic, transport-independent kinetic parameters for the solvolysis of lignin, hemicellulose, and cellulose upon incorporation of feedstock characteristics for the methanol-based extraction of poplar as an example fractionation process.

View Article and Find Full Text PDF