Publications by authors named "M J Pascoe"

Background: Speech-language pathologists (SLPs) in non-English speaking countries face challenges when assessing children for speech sound disorders (SSD). Exploring their clinical challenges in service delivery-along with their problem-solving approaches-may contribute to the development of instruments for clinical use in such settings.

Aim: The study aimed to explore assessment methods used by Iranian SLPs to identify children with SSD.

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  • Radiation therapy is a common treatment for primary brain tumors, but it may lead to significant sleep disorders that haven't been fully explored.
  • A systematic review analyzed 38 studies involving nearly 2,948 patients, finding a high incidence of sleep disturbances particularly from the end of radiation to six months afterward, linked to radiation dosage.
  • The review calls for more research on sleep disorders in patients with primary brain tumors and suggests that pharmacological interventions can help manage sleep symptoms, despite inconsistencies in how these symptoms are reported across studies.
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  • Primary care clinicians can effectively screen for sleep issues, assist patients when possible, and refer complex cases to specialists.
  • Poor sleep impacts nearly all organ systems and contributes to various health problems, highlighting the need for routine examination of sleep quality and duration in primary care.
  • The text discusses ways to enhance support and compensation for primary care providers to improve their ability to address patients' sleep concerns through meaningful conversations.
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Thiamine-responsive megaloblastic anaemia (TRMA) is a rare autosomal recessive disorder characterised by the clinical triad of megaloblastic anaemia, sensorineural hearing loss and diabetes mellitus (DM) in young patients. We present a case of a young man with type 1 DM who presented with pancytopenia of unclear aetiology, initially attributed to a COVID-19 infection. After obtaining a bone marrow biopsy and pursuing genetic testing, two pathogenic variants of the SLC19A2 gene consistent with TRMA were discovered in this patient.

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  • Untreated obstructive sleep apnea (OSA) in acute ischemic stroke (AIS) patients increases health risks, making diagnosis and treatment difficult in this demographic.
  • The study involved 27 AIS inpatients at Cleveland Clinic, where portable monitoring (PM) was used to identify OSA, and those with severe cases were offered therapy called auto-titrating positive airway pressure (APAP).
  • Despite high ratings for ease of use of the PM device, only a small percentage of patients continued using the APAP treatment consistently, revealing significant barriers and the need for more research on better screening and treatment strategies for OSA in AIS patients.
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