Publications by authors named "M J P Rooijakkers"
Importance: Heyde syndrome is the cooccurrence of aortic stenosis and gastrointestinal bleeding secondary to vascular lesions, including angiodysplasias. Several studies have demonstrated cessation of gastrointestinal bleeding after transcatheter aortic valve implantation (TAVI), but the etiology and effects on vascular lesions are largely unknown.
Objective: To examine the associations of TAVI with gastrointestinal vascular lesions and identify factors associated with recovery among patients with iron deficiency anemia and severe aortic stenosis.
Article Synopsis
- - The study evaluated the safety and efficacy of using an upper-extremity approach for secondary access during transfemoral transcatheter aortic valve implantation (TAVI) compared to the traditional lower-extremity method, as it may reduce significant bleeding risks.
- - Conducted between November 2022 and November 2023 in the Netherlands, the TAVI XS trial involved 238 patients with severe aortic stenosis, who were randomly assigned to either the upper or lower access groups.
- - Results showed that the upper-extremity approach had a lower incidence of clinically relevant bleeding (4.2% vs. 13.4% for the lower extremity), suggesting it could be a safer option for patients undergoing
Background: Paravalvular regurgitation (PVR) is a common complication after transcatheter aortic valve replacement, posing an increased risk of heart failure and mortality. Accurate intraprocedural quantification of PVR is challenging. Both hemodynamic indices and videodensitometry can be used for intraprocedural assessment of PVR.
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- * In a trial with 858 patients, results showed no significant difference in major complications between those who continued anticoagulation (16.5% experienced primary outcomes) and those who interrupted it (14.8%).
- * Continuation of anticoagulation led to higher incidences of major bleeding (31.1% vs. 21.3%), suggesting that interrupting anticoagulation is safer in this patient population undergoing TAVI.
Paravalvular regurgitation after transcatheter aortic valve replacement: incidence, quantification, and prognostic impact.
Eur Heart J Imaging Methods Pract
April 2024
Transcatheter aortic valve replacement (TAVR) is the standard of care in aortic stenosis with results comparable to surgical aortic valve replacement. However, paravalvular regurgitation (PVR) is more common after TAVR. With the alteration of devices and implantation techniques, the incidence of moderate or more PVR has declined.
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