18F-Sodium Fluoride PET/CT as a Tool to Assess Enthesopathies in X-Linked Hypophosphatemia.

X-linked hypophosphatemia (XLH) is a rare metabolic disorder characterized by elevated FGF23 and chronic hypophosphatemia, leading to impaired skeletal mineralization and enthesopathies that are associated with pain, stiffness, and diminished quality of life. The natural history of enthesopathies in XLH remains poorly defined, partly due to absence of a sensitive quantitative tool for assessment and monitoring. This study investigates the utility of 18F-NaF PET/CT scans in characterizing enthesopathies in XLH subjects.

Unplanned Reoperation After Anatomical Pulmonary Resection for Lung Cancer: Rate, Risk Factors, Early Outcomes and Long-term Prognostic Influence Within a Prospective Multicentre Database.

Objectives: The study aimed to identify perioperative variables associated with unplanned reoperation (UR) following anatomical pulmonary resection for lung cancer and investigate its impact on long-term prognostic outcomes.

Methods: The records of patients who underwent anatomical pulmonary resection for lung cancer from December 2016 to March 2018 within a nationwide prospective registry were reviewed. Multivariable logistic regression analyses were performed to find the risk factors for UR.

Standardization of the use of opsonized zymosan as stimulus in the 1,2,3-dihydrorhodamine technique for the assessment of neutrophil respiratory burst.

Introduction: Chronic granulomatous disease is a defect in phagocytosis due to deficiency of gp91phox, p22phox, p47phox, p40phox, and p67phox (classic form of the disease). Recently, EROS and p40phox deficiency were described as responsible for the non-classical form of the disease. The 1,2,3-dihydrorhodamine oxidation technique, with phorbol-12-myristate-13-acetate as a stimulus, is performed to diagnose the classic chronic granulomatous disease.

Building Family Medicine Research Through Community Engagement: Leveraging Federal Awards to Develop Infrastructure.

Many academic departments and programs struggle with the challenge of how to begin a meaningful research program. A useful place to start is with the work they already are doing in communities. Using work in practices and other clinical venues as a springboard can build helpful relationships that can catalyze research and build infrastructure that matters to family medicine clinicians, researchers, and the communities they serve.