Comparative Evaluation of Creatinine and Cystatin C Derived Glomerular Filtration Rate Methods in Hiv Patients on Therapy and Healthy Controls.

Background: Antiretroviral drugs are associated with adverse effects including chronic kidney disease. The onset of chronic kidney disease manifests with mild reduction in GFR. Early detection of chronic kidney disease is integral component of clinical medicine with major effect on disease labeling, intervention and drug dosing.

Oxidative stress markers and lipid profiles of patients with polycystic ovary syndrome in a Nigerian tertiary hospital.

Objective: To determine the activities of oxidative stress markers and lipid profiles of patients with polycystic ovary syndrome (PCOS) in Nnamdi Azikiwe University Teaching Hospital Nnewi, Nigeria.

Methods: This was a nested case-control study consisting of 50 PCOS patients and 50 healthy women of the same age range without any evidence of PCOS. The study measured the levels of malondialdehyde (MDA), activity of superoxide dismutase (SOD), glutathione peroxidase (GSH-Px), total antioxidant capacity (TAC); concentrations of total cholesterol (TC), triglycerides (TG), and low-density lipoprotein cholesterol (LDL-C), as well as high-density lipoprotein cholesterol (HDL-C) using standard spectrophotometric methods.

Lipid, lipoproteins, total antioxidant status and organ changes in rats administered high doses of cadmium chloride.

Objective: To determine the possible association between cadmium (Cd) exposure and alterations in plasma lipid and lipoprotein levels and total antioxidant status (TAS) in rats.

Materials And Method: Twenty male albino rats assigned to 2 groups of 10 rats each (test and control) were used for the study. Each test animal model was given 1.

Assessment of some renal indices in people occupationally exposed to lead.

Exposure to lead has been reported to have adverse health implications. An assessment of renal function in people occupationally exposed to lead was carried out using the following biochemical markers urea, creatinine, sodium, potassium, chloride and bicarbonate. A total of 53 test subjects (mean age 30.