Neonatal and maternal thrombocytopenia: incidence and immune background.

We performed a prospective study on the incidence of thrombocytopenia (t-penia) and its immunological origin in unselected 26,275 mothers and 24,101 newborns. Platelet antibodies were examined by the platelet immunofluorescence test (PIFT) and the monoclonal antibody immobilisation of platelet antigens assay (MAIPA). T-penia (platelet count < 100 x 10(9)/I) was found in 124 (0.

[Evaluation of granulocytes in children with malnutrition].

In 29 infants with II and III degree of undernutrition, the studies were performed of the granulocyte system including: the number of granulocytes in the bone marrow reserve pool, circulating pool, parietal and total peripheral blood, phagocytosis evaluation, NBT test and the activity of granulocytic enzymes-alkaline phosphatase and peroxidase. The following deviations were found in comparison to children of the same age with normal body weight: 1. Significant decrease of the reserve granulocyte pool in the bone marrow in children with considerable undernutrition, reaching the value of bone marrow reserve in newborn.

[Motility of polymorphonuclear leukocytes in malnutrition].

Random polymorphonuclear granulocytes motility has been studied in malnourished children, aged between one month and one year. A technique, which allowed to observe trajectories of individual cells has been applied. An analysis included the measurements of cells centres position.