Publications by authors named "M J Nijkrake"
Background: Respiratory dysfunction is an important contributor to morbidity and mortality in advanced Parkinson's disease (PD), but it is unclear what parameters are sensitive to diagnose and monitor respiratory dysfunction across disease phases.
Objectives: We aimed to characterize respiratory dysfunction in mild to moderate PD.
Methods: In 20 individuals without cardiopulmonary comorbidity, pulmonary and inspiratory muscle function testing were performed ON-medication.
Background: Debilitating problems with hand function experienced by people with Parkinson's disease (PD) can worsen during multitasking.
Purpose: To investigate the effects of dual-task interference on a pegboard task in people with mild to moderately severe PD.
Study Design: Descriptive analysis.
Objective: To investigate the feasibility and usability of an online spasticity monitoring tool amongst people with hereditary spastic paraplegia or chronic stroke receiving botulinum toxin treatment, and their healthcare providers.
Methods: Mixed methods cohort study, measuring recruitment success and adherence to the monitoring in 3 rehabilitation institutions. In addition, the System Usability Scale (SUS) and interviews with patients and their healthcare providers were used for quantitative and qualitative analysis, respectively.
Article Synopsis
- The study highlights that historical underrepresentation of females, younger individuals with Parkinson's disease (PD), and non-white populations in clinical research needs to be addressed, while also emphasizing the importance of studying non-motor symptoms.
- Investigators analyzed a dataset from a Dutch center, looking at trends in female participation, mean age, native Dutch representation, ethnicity reporting, and the assessment of non-motor symptoms over a 19-year period (2003-2021).
- Findings show no significant changes in demographics over time, indicating a consistent mean age of 66 years and a 39% female representation; however, older and non-native Dutch individuals remain underrepresented, highlighting the need for more diverse research subjects in
Background: Abnormal respiratory function tests can be observed early in the course of Parkinson's disease (PD). A better understanding of the impact of respiratory dysfunction on daily life in PD is needed to prevent later occurring complications as a (aspiration) pneumonia.
Objective: To explain which respiratory symptoms people with PD or a form of atypical parkinsonism experience and how these symptoms impact on their daily lives.