Publications by authors named "M J Naya"

An 81-year-old woman undergoing B-cell depletion therapy developed COVID-19 and a hyperglycemic hyperosmotic state. She had a history of multiple vaccinations against coronaviruses but had persistent antigen positivity. Strategies to prevent the development of COVID-19 in immunosuppressed patients have not been established.

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Definitions of cardiac sarcoidosis (CS) differ among guidelines. Any systemic histological finding of CS is essential for the diagnosis of CS in the 2014 Heart Rhythm Society statement, but not necessary in the Japanese Circulation Society 2016 guidelines. This study aimed to reveal the differences in outcomes by comparing 2 groups, namely CS patients with or without systemic histologically proven granuloma.

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Article Synopsis
  • Myocardial flow reserve (MFR) and ischemia severity are important for predicting major cardiovascular events (MACEs) in patients with coronary artery disease.
  • A study involving 640 patients categorized into three groups based on ischemia severity found that impaired MFR is a significant predictor for MACEs in those with minimal to mild ischemia but not in those with moderate-to-severe ischemia.
  • These findings suggest that assessing MFR can help clinicians effectively stratify risk in patients with lower levels of myocardial ischemia.
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: Recent advances in cardiac modalities contribute to the guidelines on the diagnosis of cardiac sarcoidosis (CS) updated by the Japanese Circulation Society. The multicenter registry, Japanese Cardiac Sarcoidosis Prognostic (J-CASP) study tried to reveal recent trends of diagnosis and outcomes in CS patients and to validate the non-invasive diagnostic approach, including cardiac F-fluorodeoxyglucose (FDG) study. : Databases from 12 hospitals consisting of 231 CS patients (mean age, 64 years; female, 65%; LV ejection fraction, 47%) diagnosed by the guidelines with FDG positron emission tomography (PET) study were integrated to compile clinical information on the diagnostic criteria and outcomes.

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