Publications by authors named "M J N L Benders"

Objective: To systematically review the literature on the associations between electroencephalogram (EEG) and brain magnetic resonance imaging (MRI) measures in preterm infants (gestational age < 37 weeks).

Methods: A comprehensive search was performed in PubMed and EMBASE databases up to February 12th, 2024. Non-relevant studies were eliminated following the PRISMA guidelines.

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In term neonates with hypoxic-ischemic encephalopathy (HIE), cerebellar injury is becoming more and more acknowledged. Animal studies demonstrated that Purkinje cells (PCs) are especially vulnerable for hypoxic-ischemic injury. In neonates, however, the extent and pattern of PC injury has not been investigated.

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Objective: Few studies have evaluated the efficacy of antiseizure medications (ASMs) according to the etiology of neonatal acute provoked seizures. We aimed to investigate the response to ASMs in term/near term neonates with acute arterial ischemic stroke (AIS), as well as the type of seizure at presentation and the monitoring approach.

Methods: We retrospectively evaluated neonates from 15 European level IV neonatal intensive care units who presented with seizures due to AIS and were monitored by continuous electroencephalography (cEEG) and/or amplitude-integrated EEG (aEEG) in whom actual recordings, timing, doses, and response to ASMs were available for review.

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Article Synopsis
  • - Cognitive developmental delays, such as severe intellectual disability (IQ < 70) and borderline intellectual functioning (IQ 70-85), create significant challenges and costs, stressing the importance of early diagnosis and intervention.
  • - High-risk groups for these delays include children with neonatal complications, congenital anomalies, and genetic disorders, but over half of cases remain unexplained, necessitating a better understanding of prognosis and functioning.
  • - This review highlights the potential of using MRI to identify brain developmental markers, particularly in white matter, to improve prognostic assessments for children with cognitive developmental delay, aiming for enhanced strategies for intervention.
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Background: Parents often perceive the news that their child has cerebral palsy (CP) as overwhelming and shocking. They are at increased risk of parental stress and mental health problems, which in turn can affect the interaction between the parent and the child. Parental mental health outcomes are known to be affected by the process of disclosure of a diagnosis.

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