Publications by authors named "M J Moesker"
Objective: Opioids are increasingly prescribed and frequently involved in adverse drug events (ADEs). The underlying nature of opioid-related ADEs (ORADEs) is however understudied. This hampers our understanding of risks related to opioid use during hospitalisation and when designing interventions.
View Article and Find Full Text PDFBackground: Bridging anticoagulation is used in vitamin-K antagonist (VKA) patients undergoing invasive procedures and involves complex risk assessment in order to prevent thromboembolic and bleeding outcomes.
Objectives: Our aim was to assess guideline compliance and identify factors associated with bridging and especially, non-compliant bridging.
Methods: A retrospective review of 256 patient records in 13 Dutch hospitals was performed.
Objectives: Surgery in patients on anticoagulants requires careful monitoring and risk assessment to prevent harm. Required interruptions of anticoagulants and deciding whether to use bridging anticoagulation add further complexity. This process, known as perioperative anticoagulant management (PAM), is optimised by using guidelines.
View Article and Find Full Text PDFAntithrombotic drugs are consistently involved in medication-related adverse events (MRAEs) in hospitalized patients. We aimed to estimate the antithrombotic-related adverse event (ARAE) incidence between 2008 and 2016 and analyse their clinical context in hospitalized patients in The Netherlands. A post-hoc analysis of three national studies, aimed at adverse event (AE) identification, was performed.
View Article and Find Full Text PDFArticle Synopsis
- The study investigates preoperative anticoagulation management (PAM) using the Functional Resonance Analysis Method (FRAM) to understand how complex processes can succeed in real-world practice compared to set guidelines.
- Conducted in a Cardiothoracic Surgery Department in Australia and Europe, the research involved interviews with 18 professionals to create models reflecting actual workflows and validate them with staff input.
- Findings revealed discrepancies between imagined and actual workflow, highlighting local adaptations for safety and opportunities for system improvements, with a total estimated workload of 47 hours for PAM processes at both sites.