Publications by authors named "M J McMenamy"

Article Synopsis
  • * Laboratory tests confirmed the presence of a low-pathogenicity avian influenza virus (LPAIV) subtype H6N1, affecting 15 premises in Northern Ireland and spreading to 13 in the Republic of Ireland and six in Great Britain.
  • * The outbreak resulted in the culling of over 2 million birds to control the spread, highlighting the significant economic consequences and the need for swift action during LPAIV outbreaks.
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Since 2020, the United Kingdom and Europe have experienced annual epizootics of high-pathogenicity avian influenza virus (HPAIV). The first epizootic, during the autumn/winter of 2020-2021, involved six H5Nx subtypes, although H5N8 HPAIV dominated in the United Kingdom. While genetic assessments of the H5N8 HPAIVs within the United Kingdom demonstrated relative homogeneity, there was a background of other genotypes circulating at a lower degree with different neuraminidase and internal genes.

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Article Synopsis
  • Bovine herpesvirus 1 (BoHV-1) causes serious respiratory disease in cattle, yet there's limited understanding of how it affects gene expression during infection.
  • This study analyzed the blood transcriptome of dairy calves infected with BoHV-1, identifying 488 genes that were significantly different in expression between infected and control groups, pointing towards key immune pathways involved.
  • The findings suggest potential new targets for treating BoHV-1, and revealed both similarities and differences when comparing the immune responses to another pathogen, BRSV, in bovine respiratory disease.
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