Publications by authors named "M J McAvoy"

Background: Spetzler-Martin (SM) Grade III brain arteriovenous malformations (BAVMs) represent a transitional risk zone between low- and high-grade BAVMs, characterized by diverse angioarchitecture. The primary treatment options are endovascular embolization, microsurgical resection (MS), and stereotactic radiosurgery (SRS). This study compares the efficacy and outcomes of MS and SRS.

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Background: Arteriovenous malformations (AVMs) are uncommon cerebral lesions that can cause significant neurological complications. Surgical resection is the gold standard for treatment, but endovascular embolization and stereotactic radiosurgery (SRS) are viable alternatives.

Objective: To compare the outcomes of endovascular embolization versus SRS in the treatment of AVMs with Spetzler-Martin grades I-III.

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Article Synopsis
  • Current treatments for intracranial aneurysms are mainly surgical or endovascular, but not all aneurysms can be treated this way.
  • Research suggests that targeting specific molecular pathways linked to aneurysm development, particularly through low frequency mutations in cancer-related genes, may lead to better outcomes.
  • This review discusses the role of these somatic variants in aneurysm pathogenesis and explores potential gene therapy techniques, including targeted delivery of chemotherapeutics.
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Article Synopsis
  • The study looked at brain injuries caused by things that penetrate the skull and how common they are in people who were hurt, particularly focusing on 73 patients.
  • The researchers compared two imaging tests, CT angiography (CTA) and digital subtraction angiography (DSA), to see which one is better at finding these injuries.
  • They found that many patients had brain blood vessel injuries, and CTA didn't find enough of them, meaning DSA should be used regularly for better diagnosis.
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Volumetric analysis methods continue to enjoy great popularity in the analysis of task-related functional MRI (fMRI) data. Among these methods, the software package FSL (FMRIB, Oxford, UK) is omnipresent throughout the field. However, it remains unknown what advantages might be gained by integrating FSL with alternative preprocessing tools.

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