Publications by authors named "M J Manrique"
Facial nerve dysfunction (FND) is a well-recognized but poorly documented complication of mandibular distraction osteogenesis (MDO) for Robin sequence (RS). This study aims to document the authors' experiences with FND and identify risk factors associated with this adverse event. A retrospective review of a prospectively gathered database was performed to identify patients with RS who underwent MDO at the authors' institution from March 2016 to June 2023.
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- Histoplasmosis is particularly dangerous for HIV patients, especially where antiretroviral therapy is hard to get, making antigen detection assays vital for quick diagnoses and reducing mortality.
- The study assessed 27 HIV patients with histoplasmosis over 24 weeks, monitoring urinary Histoplasma antigen levels as they received treatment with amphotericin B followed by itraconazole.
- Results indicated that as antigen levels decreased, patient clinical outcomes improved, suggesting that the clarus Histoplasma GM EIA kit could effectively monitor treatment responses, despite some patients having atypical antigen patterns due to immune system responses or medication absorption issues.
The Third Mobile Window Syndrome: A Clinical Spectrum of Different Anatomical Locations-Characterization, Therapeutic Response, and Implications in the Development of Endolymphatic Hydrops.
J Clin Med
November 2024
Multiple dehiscences of the otic capsule can exhibit behavior similar to Ménière's disease, not only from a clinical perspective but also in the results of audiovestibular tests. The main objective of this study is to characterize third mobile window etiologies from an audiovestibular perspective, while also evaluating the therapeutic response to four different treatment protocols. Furthermore, we aim to explore a potential association with the development of radiologically defined endolymphatic hydrops (EH).
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- This study explores the outcomes and management of pediatric auditory brainstem implantation (ABI) for children with severe inner ear malformations, aiming to unify clinical practices and address current challenges.
- A systematic review of relevant findings from the Third International Pediatric ABI Symposium analyzed data from multiple countries, highlighting trends in auditory outcomes, surgical approaches, and rehabilitation strategies.
- Key conclusions emphasize the need for standardized guidelines and improved collaboration among healthcare professionals to enhance patient outcomes and guide future research in this specialized field.
Background: Intravitreal injection of anti-vascular endothelial growth factor (anti-VEGF) agents is used to treat posterior type 1 retinopathy of prematurity (ROP). Recent reports indicate that anti-VEGF therapy may be associated with white matter brain injury, according to animal studies, and neurodevelopmental impairments in children born preterm. We investigated whether type 1 ROP treated with bevacizumab is associated with structural brain injury on infant term magnetic resonance images (MRIs) in very low birth weight infants compared with those treated with laser ablation.
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