Publications by authors named "M J Mallat"

Background: Post-surgical recovery following spine surgeries poses challenges for Muslim patients wishing to resume Salah (Islamic prayer), which involves physical movements like kneeling and prostration. This study aims to examine spine surgeons' perspectives on the appropriate timing and conditions for resuming Salah after spine surgery without restrictions.

Methods: This cross-sectional survey study included surgeons in Saudi Arabia who perform spine surgeries.

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  • BK polyomavirus-associated nephropathy (BKPyVAN) is a significant complication after kidney transplantation, usually managed by reducing immunosuppression when BK polyomavirus (BKPyV) is detected.
  • A study involving 1,076 kidney transplant recipients found a higher risk of developing de novo donor-specific antibodies (dnDSA) in patients with high BKPyV DNA loads compared to those without, suggesting that the required immunosuppression reduction can worsen immune responses.
  • While high BKPyV DNAemia increased dnDSA risk, there was no significant difference in the occurrence of biopsy-proven acute rejection (BPAR) between groups, indicating a need for better strategies to manage BKPyV infections in transplant patients.
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  • Scientists discovered that using special genes (called OSKM) can make old cells younger and help them think better.
  • They tested this on older rats and found that the ones treated with OSKM did better in memory tests than those that didn't get the treatment.
  • The OSKM treatment didn't cause any harm, and it also changed the DNA in the rats' brains in a way that showed signs of "youthfulness."
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Background: Biomechanical research demonstrates increased subscapularis abduction range of motion (ROM) when the tendon's upper two-thirds is repaired over-the-top of the center of rotation during reverse shoulder arthroplasty (RSA). This study compares the clinical outcomes of patients undergoing RSA with over-the-top subscapularis repair (OTTR) to patients without repair.

Methods: We retrospectively reviewed 97 consecutive RSAs with either OTTR of the subscapularis (N = 75) or no repair (N = 22).

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There is converging evidence that young blood conveys cells, vesicles, and molecules able to revitalize function and restore organ integrity in old individuals. We assessed the effects of young plasma on the lifespan, epigenetic age, and healthspan of old female rats. Beginning at 25.

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