Publications by authors named "M J Maciel"

Probiotics are microorganisms that provide health benefits at adequate doses and exhibit notable antioxidant and antimicrobial activities. These properties play crucial roles in combating chronic diseases linked to oxidative stress and antimicrobial resistance. This review aimed to summarize the antioxidant and antimicrobial properties of probiotics determined in in vitro studies and discuss mechanistic actions and analysis methods.

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Article Synopsis
  • Infections from the dengue virus, Orthoflavivirus denguei, can show no symptoms or a range of clinical signs due to its complex interactions with viral and host factors.
  • The study examined specific genetic variations (SNPs) in the interleukin-10 (IL-10) gene among 333 individuals in northeastern Brazil to see how they relate to symptomatic dengue.
  • Findings revealed that certain genotypes and the G allele of the -1082 A/G SNP are associated with a higher risk of developing symptomatic dengue, particularly in contrast to those with asymptomatic infections.
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This paper demonstrates the potential of Raman spectroscopy for differentiating neoplastic from non-neoplastic colon tumors, obtained with the CAM (chicken chorioallantoic membrane) model. For the CAM model two human cell lines were used to generate two types of tumors, the RKO cell line for neoplastic colon tumors and the NCM460 cell line for non-neoplastic colon tumors. The Raman spectra were acquired with a 785 nm excitation laser.

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Background: Sickle cell anemia (SCA) is the most common hemoglobinopathy in Brazil and worldwide and is part of a group of chronic genetic diseases resulting from abnormalities in the structure of hemoglobin.

Aim: To evaluate the impact of oral health conditions on the quality of life (QoL) of children and adolescents with SCA.

Design: This is a cross-sectional study with a sample of 76 children and adolescents aged 8-14 years.

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