Publications by authors named "M J M Rodriguez-Zuniga"
Objective: The objective of this study was to investigate whether glycated hemoglobin (HbA1c) is a valid surrogate for evaluating the effectiveness of antihyperglycemic drugs in diabetes mellitus (DM) trials.
Methods: We conducted a systematic review of placebo-controlled randomized clinical trials (RCTs) evaluating the effect of a treatment on HbA1c (mean difference between groups) and clinical outcomes (relative risk of mortality, myocardial infarction, stroke, heart failure, and/or kidney injury) in patients with DM. Then, we investigated the association between treatment effects on HbA1c and clinical outcomes using regression analysis at the trial level.
[Not Available].
Rev Peru Med Exp Salud Publica
September 2020
The Instituto de Evaluación de Tecnologías en Salud e Investigación (IETSI) of the Seguro Social de Salud (EsSalud) has completed seven brief reports by means of rapid reviews of evidence regarding the potentially effective therapies against SARS-CoV-2 in order to provide current and relevant information for decision makers, clinicians, researchers and the academic community in Peru. The therapeutic agents evaluated were chloroquine/hydroxychloroquine, lopinavir/ritonavir, tocilizumab, oseltamivir, interferon, atazanavir and anti SARS-CoV-2 serum. Evidence identification included the review of PubMed and Cochrane Library electronic databases.
View Article and Find Full Text PDFArticle Synopsis
- Pyoderma gangrenosum is a chronic skin condition marked by ulcers, linked to an abnormal immune response, with no universally accepted diagnostic or treatment methods.
- In Latin America, diagnosing this condition is complicated by the prevalence of similar bacterial and non-bacterial infections, with Brazil, Mexico, Argentina, and Chile reporting the highest number of cases.
- The ulcerative form is most common and is often associated with conditions like inflammatory bowel disease, with treatments primarily involving systemic corticosteroids and cyclosporine, while biological therapy remains underutilized.
Association Between Hidradenitis Suppurativa and Metabolic Syndrome: A Systematic Review and Meta-analysis.
Actas Dermosifiliogr (Engl Ed)
May 2019
Background: Recent studies have shown a relationship between hidradenitis suppurativa (HS) and metabolic syndrome (MS), but the literature offers no meta-analysis restricted to studies that have been adjusted for confounders.
Objective: To determine the association between HS and MS.
Methods: A systematic review and meta-analysis of observational studies on HS and MS in adults.
Background: There is a lack of evidence to support acyclovir administration in pityriasis rosea.
Objective: To determine the efficacy of acyclovir in patients with typical pityriasis rosea.
Methods: A systematic review and meta-analysis of experimental studies was performed in MEDLINE, SCOPUS, EMBASE and others, from January 1990 to October 2016 on acyclovir for pityriasis rosea.