Regression of human papillomavirus intraepithelial lesions is induced by MVA E2 therapeutic vaccine.

Human papilloma viruses can induce warts, condylomas, and other intraepithelial cervical lesions that can progress to cancer. Cervical cancer is a serious problem in developing countries because early detection is difficult, and thus proper early treatment is many times missing. In this phase III clinical trial, we evaluated the potential use of MVA E2 recombinant vaccinia virus to treat intraepithelial lesions associated with papillomavirus infection.

Identification of different nutritional status groups in institutionalized elderly people by cluster analysis.

Objectives: To apply a cluster analysis to groups of individuals of similar characteristics in an attempt to identify undernutrition or the risk of undernutrition in this population.

Design: A cross-sectional study.

Setting: Seven public nursing homes in the province of Murcia, on the Mediterranean coast of Spain.

Nutrition and prevalence of undernutrition assessed by different diagnostic criteria in nursing homes for elderly people.

Background: Undernutrition is the state produced by the intake of insufficient energy, macronutrients or micronutrients. The present study aimed to assess the prevalence of undernutrition using 10 different diagnostic criteria described in the literature and to assess its association with energy intake in an institutionalised elderly population.

Methods: The cross-sectional study included 213 subjects, aged 65-96 years (135 women and 78 men), who lived in seven nursing homes in the province of Murcia, on the Mediterranean coast of Spain.

Dietary intake and iron status of institutionalized elderly people: relationship with different factors.

Objectives: Aims of the study were to investigate iron status in institutionalized elderly subjects and to determine its association with different factors including: age, gender, body mass index, dietary intake, consumption of iron supplements, functional status and disease.

Design: A cross-sectional study.

Setting: Seven public nursing homes.

Seemingly paradoxical seasonal influences on vitamin D status in nursing-home elderly people from a Mediterranean area.

Objective: We investigated vitamin D status in institutionalized elderly subjects by measuring serum 25-hydroxyvitamin D (25[OH]D) and its association with season and other factors: age, gender, nutritional status, cognitive function, functional ability, dietary intake, vitamin D supplement consumption, and disease.

Methods: The cross-sectional study included 86 subjects, 65-94 y of age (29 men and 57 women), who lived in three nursing homes in Murcia, a Spanish Mediterranean area. The Mini Nutritional Assessment, Short Portable Mental Status Questionnaire, and BI were used to evaluate nutritional status, functional ability, and cognitive function, respectively.