Publications by authors named "M J Legrand"
Background: Upper limb impairment post-stroke often leads to a predominant use of the less affected arm and consequent learned disuse of the affected side, hindering upper limb outcome. Wearable sensors such as accelerometers, combined with smart reminders (i.e.
View Article and Find Full Text PDFDysregulation of the renin-angiotensin-aldosterone-system (RAAS) in sepsis is a complex and early phenomenon with a likely significant contribution to organ failure and patient outcomes. A better understanding of the pathophysiology and intricacies of the RAAS in septic shock has led to the use of exogenous angiotensin II as a new therapeutic agent. In this review, we report a multinational and multi-disciplinary expert panel discussion on the role and implications of RAAS modulation in sepsis and the use of exogenous angiotensin II.
View Article and Find Full Text PDFArticle Synopsis
- About 62.3% of critically ill patients admitted for sepsis developed acute kidney injury (SA-AKI) during their hospital stay.
- The study found that severe SA-AKI significantly increased the risk of in-hospital mortality among these patients.
- Proper hydration and fluid resuscitation within the first hour of treatment were linked to lower mortality rates in patients with severe SA-AKI.