In recent years, optical temperature probes operating in the second near-infrared (BW-II) and third near-infrared (BW-III) biological windows have garnered significant attention in the scientific community. For biological applications these probes offer distinct advantages, including enhanced tissue penetration depth, minimal autofluorescence, and a remarkable improvement in imaging sensitivity and spatial resolution. Moving toward theranostic applications, there is a growing demand for the development of materials that integrate both BW-II and BW-III thermometry systems with drug delivery functionalities.
View Article and Find Full Text PDFThe most efficient upconversion (UC) materials reported to date are based on fluoride hosts with low phonon energies, which reduce the amount of nonradiative transitions. In particular, NaYF doped with Yb and Er at appropriate ratios is known as one of the most efficient UC phosphors. However, its low thermal stability limits its use for certain applications.
View Article and Find Full Text PDFObjectives: This study assessed the content of US Medical Licensing Examination question banks with regard to out-of-hospital births and whether the questions aligned with current evidence.
Methods: Three question banks were searched for key words regarding out-of-hospital births. A thematic analysis was then utilized to analyze the results.
The RAVER1 protein serves as a co-factor in guiding the polypyrimidine tract-binding protein (PTBP)-dependent control of alternative splicing (AS). Whether RAVER1 solely acts in concert with PTBPs and how it affects cancer cell fate remained elusive. Here, we provide the first comprehensive investigation of RAVER1-controlled AS in cancer cell models.
View Article and Find Full Text PDF