A Mnemonic for Effective "Lesss PAINFUL" Pre-Rounding.

Due to much of medical training being inpatient centered, medical trainees generally do more pre-rounding on a per-patient basis than they do complete histories and physical exams (H&Ps). However, formal training often overlooks pre-rounding as a critical aspect of medical education and patient care, with at least 10 times more publications on H&Ps than on any other aspect of rounding over the past half-century. To address this critical gap in medical education, we introduce the "Lesss PAINFUL" pre-rounding mnemonic, emphasizing the importance of efficient pre-rounding for medical students or other trainees.

Peer-Led Adjunctive Interventions for Increasing the Reach of HIV Prevention and Care Interventions to Latino/x/e Men Who Have Sex with Men: a Scoping Review.

Purpose Of Review: Latino/x/e men who have sex with men (LMSM) in the United States are disproportionately affected by HIV. Peer-led adjunctive interventions show promise for enhancing engagement in HIV prevention and care among LMSM, but their effectiveness and implementation remain underexplored. This scoping review aimed to map existing evidence on peer-led interventions, identify gaps, and inform future research for enhancing HIV prevention and care among LMSM.

Persistent Toughness and Heat Triggered Plasticization in Polylactide Modified with Poly(ethylene oxide)--poly(butylene oxide).

Poly(lactide) (PLA) is a promising biodegradable polymer with potential applications in single-use packaging. However, its use is limited by brittleness, and its biodegradability is restricted to industrial compost conditions due in part to an elevated glass transition temperature (). We previously showed that addition of a poly(ethylene-oxide)--poly(butylene oxide) diblock copolymer (PEO-PBO) forms macrophase-separated rubbery domains in PLA that can impart significant toughness at only 5 wt %.

Associations of plasma extracellular microRNAs with new-onset breast cancer in the Framingham heart study.

Breast cancer is the second leading cause of cancer deaths among women. Multiple microRNAs (miRNAs) have been reported to be associated with breast cancer progression or metastasis. The purpose of the current study was to identify plasma extracellular miRNAs associated with incident breast cancer.

Stability of performance monitoring with prolonged task performance: A study of error-related negativity and error positivity.

The use of forced-choice response tasks to study indices of performance monitoring, such as the error-related negativity (ERN) and error positivity (Pe), is common, and such tasks are often used as a part of larger batteries in experimental research. ERN amplitude typically decreases over the course of a single task, but it is unclear whether amplitude changes persist beyond a single task or whether Pe amplitude changes over time. This preregistered study examined how prolonged task performance affects ERN and Pe amplitude across two study batteries, each with three different tasks.