Abnormal c-Fos expression in TetTag mice containing fos-EGFP.

Molecular and genetic techniques now allow selective tagging and manipulation of the population of neurons, often referred to as "engram cells," that were active during a specific experience. One common approach to labeling these cells is to use the transgenic mouse (TetTag). In addition to tagging cells active during learning, it is common to examine the reactivation of these cells using immediate early gene (IEG) expression as an index of neural activity.

Rare earth elements accumulation and patterns in abiotic and biotic compartments of a large river system influenced by natural and anthropogenic sources in Eastern Canada.

The mobilization of rare earth elements (REEs) in aquatic ecosystems is expected to rise significantly due to intensified exploitation, erosion, and climate change. As a result, more attention has been brought to study their environmental fate. However, our ability to assess contamination risks in freshwater organisms remains limited due to scarce data on the composition and accumulation of REEs.

Value-based comparison of ambulatory children with respiratory diseases in an emergency department and a walk-in clinic: a retrospective cohort study in Québec, Canada.

Objective: To compare health outcomes and costs given in the emergency department (ED) and walk-in clinics for ambulatory children presenting with acute respiratory diseases.

Design: A retrospective cohort study.

Setting: This study was conducted from April 2016 to March 2017 in one ED and one walk-in clinic.