Publications by authors named "M J Laforest"
Separase regulates multiple aspects of the metaphase-to-anaphase transition. Separase cleaves cohesin to allow chromosome segregation and localizes to vesicles to promote exocytosis. The anaphase-promoting complex/cyclosome (APC/C) activates separase by ubiquitinating its inhibitory chaperone, securin, triggering its degradation.
View Article and Find Full Text PDFCover crops, a soil conservation practice, can contribute to reducing disease pressure caused by , considered one of the most important bacterial plant pathogens. We recently demonstrated that the phyllosphere (leaf surface) bacterial community structure changed when squash () was grown with a rye () cover crop treatment, followed by a decrease of angular leaf spot disease symptoms on squash caused by pv. .
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- Ambrosia artemisiifolia and Ambrosia trifida are significant pest species and major sources of allergens worldwide; this study presents detailed genome assemblies for both species using a hybrid approach.
- The genome assemblies reveal high completeness and substantial repetitive elements, with a notable number of genes related to herbicide resistance and allergenicity, indicating resilience against glyphosate.
- The structural evolution of A. trifida shows more genome rearrangements, while A. artemisiifolia exhibits stable genetic structures, providing insights into the evolutionary history of these allergenic plants within the Heliantheae Alliance.
Separase is a key regulator of the metaphase to anaphase transition with multiple functions. Separase cleaves cohesin to allow chromosome segregation and localizes to vesicles to promote exocytosis in mid-anaphase. The anaphase promoting complex/cyclosome (APC/C) activates separase by ubiquitinating its inhibitory chaperone, securin, triggering its degradation.
View Article and Find Full Text PDFBackground: Distance simulation is defined as simulation experiences in which participants and/or facilitators are separated from each other by geographic distance and/or time. The use of distance simulation as an education technique expanded rapidly with the recent COVID-19 pandemic, with a concomitant increase in scholarly work.
Methods: A scoping review was performed to review and characterize the distance simulation literature.