Language and the young stutterer: a new look at old theories and findings.

The major theories and research approaches as to the etiology and development of stuttering are reviewed from a historical perspective. Findings are drawn from different sources indicating that language deficits are an initial contributing factor and a continuing component of this disorder. Those subsets of children which constitute high-risk groups are identified.

Olfactory esthesioneuroblastoma--variables predictive of tumor control and recurrence.

This report surveys the world literature concerning prognostic variables for patients with esthesioneuroblastoma, an uncommon tumor arising from the olfactory epithelium. Specific sites of local and regional tumor extension, recurrence of disease after treatment, distant metastasis, and patient age were all found to be related to patient prognosis. There is a higher cure rate for patients treated after 1966, indicating an improvement in treatment methods.

Response of mouse kidney to hyperthermia: pathology and temperature--dependence of injury.

Hyperthermia either alone or in combination with radiotherapy and chemotherapy is being used increasingly in the treatment of malignant tumors. This study was designed to evaluate the response of the mouse kidney exposed to a range of hyperthermic temperatures (41 to 45 degrees C) used to induce regression of malignant tumors. Minimal histologic evidence of renal injury occurred in the proximal tubules of the subcapsular region.