Publications by authors named "M J Herron"
Article Synopsis
- Biological tissues and biomaterials typically have a fibrous microstructure that affects their physical properties and cellular behavior, which can be analyzed using specialized 3D imaging techniques to extract orientation distribution functions (ODFs).
- The research developed an algorithm and software framework for characterizing inhomogeneous ODFs in image data, incorporating them into finite element modeling to better predict material behavior.
- The new software, implemented in FEBio Studio, enhances the accuracy of simulations by utilizing true measured ODFs instead of approximations, thereby providing a more effective tool for the biomechanics and biophysics communities.
Background: Bronchoalveolar lavage (BAL) is essential in determining the efficacy of novel therapies in alpha-1 antitrypsin deficiency (AATD). These require initial proof-of-concept demonstration that treatment administration increases alpha-1 antitrypsin (AAT) levels and/or anti-neutrophil elastase inhibitory capacity (ANEC) in the lung. Early-phase studies often encounter high interindividual variability of BAL results, primarily stemming from the inherent dilution characteristics of returned BAL fluid.
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- Surgical removal of epidermoid cysts can cause "cyst spray," which is a hazard for surgeons, staff, and patients.
- Using specific methods during anesthesia can help reduce exposure to this cyst spray.
- Two effective techniques include placing an antiseptic-soaked gauze pad over the lesion and covering the cyst with a clear biohazard bag.*