Two-Step Reduction Pathway of Copper(II) by Oleylamine for the Nucleation of Cu(0) Nanoparticles: A Joint Modelling and Experimental Study.

Oleylamine is widely used in the synthesis of colloidal nanoparticles, as a solvent, as a stabilizing agent, and sometimes as a reducing agent. For example, metallic nanoparticles are obtained through reduction when Ni(II) and Pd(II) precursors are used or through disproportionation in the case of Ni(I) or Co(I). A similar dichotomy is observed for Cu precursors, with an additional complexity due to the nature of the precursor salt.

Dynamic Kinetic Resolution Processes Based on the Switchable Configurational Instability of Allenyl Copper Reagents.

The configurational instability of allenyl copper reagents is unveiled. An experimental study highlights the crucial role of Li and of the reaction temperature in the control of the configurational stability of allenyl copper reagents. A judicious choice of the reaction conditions allows efficient dynamic kinetic resolution processes and gives a one-pot access to homopropargylic alcohols or amines bearing up to four contiguous defined stereogenic centers.

Triggering Electron Transfer in Co(I) Dimers: Computational Evidences for a Reversible Disproportionation Mechanism.

An inner-sphere disproportionation mechanism of the Co(I) precursor CoCl(PPh ) is described through a Density Functional Theory study. The essential role of oleylamine in this process is unravelled. A detailed analysis of the electronic structure of Cobalt dimers of the general formula Co Cl L (L=NH and PH ) demonstrates that electron transfer is triggered by asymetric coordination of amine and phosphine to stabilize a mixed-valence Co(II)-Co(0) dimer.

Pure SARS-CoV-2 related AVDS (Acute Vascular Distress Syndrome).

Background: SARS-CoV-2 virus which targets the pulmonary vasculature is supposed to induce an intrapulmonary right to left shunt with an increased pulmonary blood flow. Such vascular injury is difficult to observe because it is hidden by the concomitant lung injury. We report here what may be, to the best of our knowledge, the first case of a pure Covid-19 related Acute Vascular Distress Syndrome (AVDS).