Publications by authors named "M J Fernandez-Reyes"
Article Synopsis
- This study explores the impact of gingivitis on inflammation and cardiovascular risks in women with polycystic ovary syndrome (PCOS).
- The research involved three groups of participants: two with PCOS (one with gingivitis and one without) and a control group, all assessed for various health indicators and inflammatory markers.
- Results indicated that PCOS patients, especially those with gingivitis, had higher levels of systemic inflammation and more aggressive neutrophil behavior, which may increase the risk of atherosclerosis.
Is there an association between periodontal disease and infertility? A systematic review.
Med Oral Patol Oral Cir Bucal
November 2024
Article Synopsis
- Idiopathic infertility affects over 186 million people globally, and its management is complicated by comorbidities; periodontal diseases may worsen infertility by increasing inflammation and insulin resistance.
- A systematic review analyzed high-quality studies involving 4,871 patients and found an association between low-grade chronic inflammation linked to periodontal diseases and idiopathic infertility conditions like obesity and type 2 diabetes.
- Results showed a higher prevalence of periodontal disease in infertile patients; mechanisms include proinflammatory responses, oxidative stress, and insulin resistance that may connect infertility with periodontal health issues.
Article Synopsis
- The concept of adequacy in peritoneal dialysis has evolved from focusing mainly on specific goals like solute clearance to prioritizing the overall quality of life for patients.
- This document aims to provide updated recommendations regarding peritoneal dialysis adequacy, covering key areas such as residual kidney function and different types of dialysis methods.
- A systematic approach (GRADE) was employed to highlight the quality of evidence for recommendations, and the document references a recent guide by experts from the International Society of Peritoneal Dialysis for additional support.
Aims/hypothesis: Alterations in circadian rhythms increase the likelihood of developing type 2 diabetes and CVD. Circadian rhythms are controlled by several core clock genes, which are expressed in nearly every cell, including immune cells. Immune cells are key players in the pathophysiology of type 2 diabetes, and participate in the atherosclerotic process that underlies cardiovascular risk in these patients.
View Article and Find Full Text PDFObjective: Type 2 diabetes (T2D) is linked to metabolic, mitochondrial and inflammatory alterations, atherosclerosis development and cardiovascular diseases (CVDs). The aim was to investigate the potential therapeutic benefits of GLP-1 receptor agonists (GLP-1 RA) on oxidative stress, mitochondrial respiration, leukocyte-endothelial interactions, inflammation and carotid intima-media thickness (CIMT) in T2D patients.
Research Design And Methods: Type 2 diabetic patients (255) and control subjects (175) were recruited, paired by age and sex, and separated into two groups: without GLP-1 RA treatment (196) and treated with GLP-1 RA (59).