Publications by authors named "M J Coyle"
Orthoflavivirus circulation in South-East Queensland, Australia, before and during the 2021-2022 incursion of Japanese encephalitis virus assessed through sero-epidemiological survey of a sentinel equine population.
One Health
December 2024
An incursion and outbreak of Japanese encephalitis virus (JEV) was reported in Australia in 2021 and 2022, respectively. There was speculation that JEV may have been circulating in Australia unknowingly prior to the detection. In this study, we determined sero-prevalence and transmission of West Nile virus (WNV), Murray Valley encephalitis virus (MVEV) and JEV, prior to and post JEV incursion in a sentinel equine population in south-east Queensland (SEQ), Australia, using blocking ELISAs (screening test) and virus neutralisation test (confirmatory).
View Article and Find Full Text PDFBackground: Pharmacy services at surgical pre-assessment clinics and on inpatient wards are well-documented, but services to theatre appear comparatively under-developed. High-risk and high-cost medicines are used routinely in theatre; pharmacists are well-qualified to optimise their use and improve patient care.
Aim: To determine the range, extent and nature of pharmacy services to theatre internationally, and to describe any reported outcomes of these services.
Article Synopsis
- Clinicians often prefer antiplatelet therapy over direct oral anticoagulants (DOACs) for atrial fibrillation due to concerns about higher risks of intracranial bleeding despite DOACs being more effective in preventing strokes.
- The study aimed to compare the risks of intracranial and major hemorrhage between DOAC therapy and single-agent antiplatelet therapy using data from nine randomized clinical trials with nearly 45,500 participants.
- Results showed no significant difference in the risk of intracranial hemorrhage between the two therapies; however, the analysis indicated variability in results among different DOACs, with rivarox