Publications by authors named "M J Cooney"
Background: An accurate knowledge of a patient's risk of cord-level intraoperative neuromonitoring (IONM) data loss is important for an informed decision-making process prior to deformity correction, but no prediction tool currently exists.
Methods: A total of 1,106 patients with spinal deformity and 205 perioperative variables were included. A stepwise machine-learning (ML) approach using random forest (RF) analysis and multivariable logistic regression was performed.
Purpose: To explore if patients' preferences regarding formalities and inpatient accommodation during their inpatient hospital experience have changed since 1999.
Methods: A ten-item survey was administered to an inpatient sample in an urban teaching hospital and compared with results from a similar survey in 1999.
Results: The majority (98.
Objectives: Waitlist times for adolescents to be seen for initial assessment for gender-affirming hormone therapy in Manitoba, Canada are often 2 years. The purpose of this study was to understand the experiences of waitlisted youth and to assess the impact of social work contact for accessing relevant resources.
Methods: A qualitative, semi-structured interview study was conducted.
A Strategy for the Formal C-N Cross-Coupling of Tertiary Amines.
Angew Chem Int Ed Engl
December 2024
Article Synopsis
- A new approach is introduced for efficiently connecting tertiary amines through C-N cross-coupling using N-acyl ammonium species.
- The process involves treating tertiary amines with TFAA or chloroformates and NaI to create alkyl iodides that can then participate in Ni-catalyzed reactions.
- This method is versatile, working for both acyclic and cyclic compounds, even complicated ones, and is demonstrated in the modification of intricate heterocyclic structures.
Purpose: To determine if an improvement in cord-level intraoperative neuromonitoring (IONM) data following data loss results in a reduced risk for new postoperative motor deficit in pediatric and adult spinal deformity surgery.
Methods: A consecutive series of 1106 patients underwent spine surgery from 2015 to 2023 by a single surgeon. Cord alerts were defined by Somatosensory-Evoked Potentials (SSEP; warning criteria: 10% increase in latency or > 50% loss in amplitude) and Motor-Evoked Potentials (MEP; warning criteria: 75% loss in amplitude without return to acceptable limits after stimulation up 100 V above baseline level).