Publications by authors named "M J Cassidy"

Study Design: Retrospective observational study.

Objective: This study analyzes the epidemiology of pediatric Le Fort fractures and assesses the incidence of concomitant injuries and acute-level hospital course using the largest, national pediatric trauma database to date.

Methods: Pediatric midface and Le Fort fractures from 2016-2019 were identified in the National Trauma Data Bank.

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Background: Our objective is to evaluate the utilization fraction (UF) of surgical instruments during a commonly performed ambulatory hand surgery case as an avenue for cost reduction, increased operating room efficiency, and systems quality improvement.

Methods: The total number of instruments opened at the start of the case was recorded followed by instruments being divided into those used and not used during the procedure. Total sterile processing costs were estimated at $1.

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Article Synopsis
  • Autoimmune diseases like rheumatoid arthritis (RA) lead to chronic inflammation, tissue damage, and pain, primarily affecting joints, especially in the hands and feet.
  • A study focused on dorsal root ganglia (DRGs) from RA patients identified 128 differentially expressed genes (DEGs) through RNA sequencing, indicating significant changes compared to non-arthritic controls.
  • The findings suggest that upregulated immune genes and those related to nerve growth may contribute to ongoing pain signaling and hypersensitivity in RA patients.
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Background: A deeper understanding of acute rejection in vascularized composite allotransplantation is paramount for expanding its utility and longevity. There remains a need to develop more precise and accurate tools for diagnosis and prognosis of these allografts, as well as alternatives to traditional immunosuppressive regimens.

Methods: Twenty-seven skin biopsies collected from 3 vascularized composite allotransplantation recipients, consisting of face and hand transplants, were evaluated by histology, immunohistochemistry staining, and gene expression profiling.

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