Publications by authors named "M J Cass"

Introduction: Non-autoimmune sacroiliac joint pain contributes to nearly a quarter of low back pain patients. Non-surgical management fails to satisfy patients. A new minimally invasive technique for sacroiliac stabilization has been introduced, defying the traditional rules of fusion.

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BACKGROUND Approximately 10% to 15% of patients with multiple myeloma (MM) are diagnosed with high-risk disease and have poor prognosis. Clinical trial data supports the combined use of selinexor, bortezomib, and dexamethasone (XVd) for treatment of patients with MM who have received at least 1 prior therapy. Information on the efficacy of XVd and of subsequent allogeneic stem cell transplantation (SCT) in heavily pretreated patients with high-risk MM is limited.

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Article Synopsis
  • Identifying suitable volunteer unrelated donors for hematopoietic cell transplantation in South Africa is difficult due to the region's diverse ethnic backgrounds, making haploidentical transplants a promising alternative for high-risk leukemia patients.
  • This study analyzed 134 patients who underwent unmanipulated haploHCT between 2014 and 2019, focusing on survival rates, mortality, and complications like acute graft-versus-host disease.
  • Results showed a 1-year overall survival rate of 56% and disease-free survival of 47%, with significant non-relapse mortality and relapse rates recorded over three years.
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With Canada's aging population, innovations in technology and changes in patient preferences regarding where they receive care, there is a growing reliance on homecare services. Professionals in the homecare sector want to provide the best care possible for their clients, whereas homecare organizations look to foster a greater patient safety culture. The Canadian Patient Safety Institute and the Canadian Home Care Association conducted two learning collaboratives aimed at increasing quality improvement capability in homecare settings.

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