Publications by authors named "M J Cala"

Accurate detection of cyanide exposure is crucial, particularly in forensic science. However, cyanide's high volatility and potential biochemical conversions in biological samples pose challenges for direct detection, complicating the determination of cause of death. Identifying alternative cyanide metabolites as markers may mitigate false negatives and positives, extending the detection window in poisoning cases.

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Flavor is the main factor driving consumers acceptance of food products. However, tracking the biochemistry of flavor is a formidable challenge due to the complexity of food composition. Current methodologies for linking individual molecules to flavor in foods and beverages are expensive and time-consuming.

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  • Patients with COVID-19 on ventilators have a higher risk of developing ventilator-associated pneumonia (VAP), which can lead to increased healthcare costs and worse outcomes.* -
  • This study analyzed the lung microbiome and immune responses in mechanically ventilated COVID-19 patients to understand the mechanisms leading to VAP, comparing samples taken shortly after intubation and 72 hours later.* -
  • Results showed differences in the microbiome related to VAP, along with higher viral loads and unique metabolic changes in patients who developed VAP, highlighting the complex interactions between microbiota, viral response, and inflammation.*
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In this study a Machine Learning model was employed to predict the lipid profile from supercritical fluid extraction (SFE) of microalgae sp. USBA-GBX-832 under different temperature (40, 50, 60°C), pressure (150, 250 bar), and ethanol flow (0.6, 0.

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  • Scientists from 34 labs in 19 countries worked together to measure certain fats (ceramides) in human blood using special techniques.
  • They used both standard methods and their own methods to get very accurate and consistent results.
  • The study helps improve future medical tests and treatments by providing reliable information about these fats in blood samples.
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