Publications by authors named "M J Budoff"

Article Synopsis
  • AI-CAC automated left atrial volumetry offers more actionable insights compared to traditional methods like the Agatston coronary artery calcium score, predicting atrial fibrillation (AF) as early as one year.
  • The study evaluated the effectiveness of AI-CAC against human-measured left atrial volumes using cardiac magnetic resonance imaging (CMRI) in predicting AF and stroke, alongside established risk scores and biomarkers.
  • Results showed that AI-CAC and CMRI provided similar predictive capabilities for AF and stroke over a 15-year period, indicating potential for AI-CAC in clinical settings, but further research is needed to confirm its utility.
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Purpose Of Review: Inflammation has been commonly known for the past decade as a part of the pathophysiology of atherosclerosis, along with lipid accumulation. However, some patients with optimized lipid-lowering therapy still have elevated inflammatory biomarkers. Anti-inflammation therapies were developed to eradicate this residual risk.

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Background: People with HIV (PWH) have benefited greatly from antiretroviral therapy, but face additional challenges from age-related comorbid conditions, particularly cardiovascular disease including venous thromboembolism (VTE). Little is known about the effect of HIV viremia and immunodeficiency on VTE risk in this population.

Methods: We assessed incident, centrally adjudicated VTE among 21,507 PWH in care between 1/2009-12/2019 within the Centers for AIDS Research Network of Integrated Clinical Systems (CNICS) cohort.

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Background: The relationship between the extent and severity of stress-induced ischemia and the extent and severity of anatomic coronary artery disease (CAD) in patients with obstructive CAD is multifactorial and includes the intensity of stress achieved, type of testing used, presence and extent of prior infarction, collateral blood flow, plaque characteristics, microvascular disease, coronary vasomotor tone, and genetic factors. Among chronic coronary disease participants with site-determined moderate or severe ischemia, we investigated associations between ischemia severity on stress testing and the extent of CAD on coronary computed tomography angiography.

Methods: Clinically indicated stress testing included nuclear imaging, echocardiography, cardiac magnetic resonance imaging, or nonimaging exercise tolerance test.

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